Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342460 | 1.00 | SLC18A3 (0.50) | SLC18A3KDM4ETP53HRH3CHRNA10 | |
| SCHEMBL7342448 | 1.00 | SLC18A3 (0.50) | SLC18A3KDM4ETP53HRH3CHRNA10 | |
| Acetic Acid SCHEMBL8003545 | 0.74 | ITGB3 (0.50) | SLC18A3 | |
| SCHEMBL5800431 | 0.74 | KDM4E (0.61) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| Acetic Acid SCHEMBL7080071 | 0.73 | SLC18A3 (0.46) | SLC18A3KDM4EKHK | |
| SCHEMBL2384959 | 0.72 | KDM4E (0.80) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL1748901 | 0.72 | KDM4E (0.58) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL7341544 | 0.72 | SLC18A3 (0.58) | SLC18A3HRH3 | |
| SCHEMBL7341548 | 0.72 | SLC18A3 (0.58) | SLC18A3HRH3 | |
| SCHEMBL7341559 | 0.72 | SLC18A3 (0.58) | SLC18A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |