Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6021382 | 0.84 | TSHR (0.53) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7353926 | 0.84 | GRIN2D (0.32) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7352678 | 0.81 | GRIN2D (0.46) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7344035 | 0.81 | GRIN2D (0.46) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7350652 | 0.81 | GRIN2D (0.38) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7351325 | 0.81 | ALDH1A1 (0.38) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7351629 | 0.79 | GRIN2D (0.48) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7350934 | 0.75 | GRIN2D (0.46) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7345815 | 0.75 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7344271 | 0.73 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005337-A1 | USE OF GABA AND NMDA RECEPTOR LIGANDS FOR THE TREATMENT OF MIGRAINE HEADACHE | COCENSYS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |