Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.77 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342705 | 0.98 | F2 (0.77) | F2F10 | |
| SCHEMBL7339989 | 0.89 | F2 (0.81) | F2F10 | |
| SCHEMBL9074186 | 0.89 | F2 (0.81) | F2F10 | |
| SCHEMBL9073910 | 0.88 | F2 (0.77) | F2F10 | |
| SCHEMBL7348819 | 0.87 | F2 (0.65) | F2F10 | |
| SCHEMBL9076756 | 0.87 | F2 (0.79) | F2 | |
| SCHEMBL7343541 | 0.87 | F2 (0.67) | F2F10 | |
| SCHEMBL7349871 | 0.87 | F2 (0.58) | F2F10 | |
| SCHEMBL9076384 | 0.86 | F2 (0.79) | F2 | |
| SCHEMBL9076745 | 0.86 | F2 (0.79) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623595-A1 | Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | claimed |
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0623595-A1 | Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |