Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074055 | 0.89 | F2 (0.58) | F2 | |
| SCHEMBL7342883 | 0.87 | F2 (0.77) | F2F10 | |
| SCHEMBL7342705 | 0.84 | F2 (0.77) | F2F10 | |
| SCHEMBL7205428 | 0.76 | F2 (0.49) | F2 | |
| SCHEMBL7341602 | 0.75 | F2 (0.44) | F2 | |
| SCHEMBL7339989 | 0.75 | F2 (0.81) | F2F10PLAU | |
| SCHEMBL9074186 | 0.75 | F2 (0.81) | F2F10PLAU | |
| SCHEMBL9073775 | 0.75 | F2 (0.48) | F2F10PLAU | |
| SCHEMBL9073910 | 0.75 | F2 (0.77) | F2F10 | |
| SCHEMBL7344650 | 0.74 | F2 (0.51) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0623595-A1 | Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |