Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337025 | 0.95 | KLKB1 (0.52) | KLKB1MMP9MMP8PPARGMME | |
| SCHEMBL7339080 | 0.91 | KLKB1 (0.58) | KLKB1KLK1 | |
| SCHEMBL7346201 | 0.87 | PPARG (0.48) | KLKB1MMP9MMP8PPARGKLK1 | |
| SCHEMBL7343062 | 0.87 | KLKB1 (0.47) | KLKB1MMP9MMP8PPARGKLK1 | |
| SCHEMBL7341933 | 0.86 | PPARG (0.50) | CYP3A4MMP9MMP8PPARGCTSS | |
| SCHEMBL7345736 | 0.86 | REN (0.51) | KLKB1MMP9MMP8PPARGCTSL | |
| SCHEMBL7348629 | 0.86 | PPARG (0.47) | ALDH1A1KLKB1MMP9MMP8PPARG | |
| SCHEMBL7344073 | 0.85 | PPARG (0.62) | MMP9MMP8PPARGMMEACE | |
| SCHEMBL7340612 | 0.85 | PPARG (0.47) | KLKB1MMP9MMP8PPARGCTSL | |
| SCHEMBL7341957 | 0.84 | PLG (0.50) | MMP9MMP8PPARGMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |