Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.53 |
| ▸ | FAP | Q12884 | 1/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343558 | 1.00 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6497247 | 0.88 | F2 (0.57) | OPRM1F2OPRD1OPRK1 | |
| SCHEMBL2119635 | 0.88 | F2 (0.57) | OPRM1F2OPRD1OPRK1 | |
| SCHEMBL2778544 | 0.88 | F2 (0.57) | OPRM1F2OPRD1OPRK1 | |
| SCHEMBL6850160 | 0.88 | F2 (0.57) | OPRM1F2OPRD1OPRK1 | |
| SCHEMBL2778546 | 0.88 | F2 (0.57) | OPRM1F2OPRD1OPRK1 | |
| SCHEMBL10722838 | 0.87 | OPRM1 (0.51) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2192304 | 0.86 | OPRM1 (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6850981 | 0.86 | F2 (0.57) | OPRM1F2OPRD1OPRK1 | |
| SCHEMBL6850997 | 0.86 | F2 (0.57) | OPRM1F2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |