Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307994 | 0.93 | HDAC8 (0.47) | PTPN1ALDH1A1HDAC8HDAC3HDAC4 | |
| SCHEMBL7315613 | 0.81 | HDAC8 (0.44) | ALDH1A1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL7322712 | 0.81 | MME (0.51) | — | |
| SCHEMBL7348038 | 0.81 | MME (0.51) | — | |
| SCHEMBL7318673 | 0.81 | HDAC1 (0.53) | GAAL3MBTL1ALDH1A1HDAC1HDAC6 | |
| SCHEMBL7312117 | 0.79 | MME (0.52) | ALDH1A1RAB9AUSP30CYP1A2CYP3A4 | |
| SCHEMBL7312109 | 0.79 | MME (0.52) | ALDH1A1RAB9AUSP30CYP1A2CYP3A4 | |
| SCHEMBL5162756 | 0.79 | USP30 (0.56) | PTPN1GAAL3MBTL1ALDH1A1HDAC8 | |
| SCHEMBL5162894 | 0.79 | USP30 (0.56) | PTPN1GAAL3MBTL1ALDH1A1HDAC8 | |
| SCHEMBL7318069 | 0.78 | MMEL1 (0.59) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |