SCHEMBL734384

SCHEMBL734384

Cc1cc(=O)oc2cc(B3OC(C)(C)C(C)(C)O3)ccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.53
ALDH1A1 P00352 10/20 0.53
KDM4E B2RXH2 8/20 0.53
HPGD P15428 6/20 0.53
HSD17B10 Q99714 6/20 0.53
GLA P06280 5/20 0.53
GAA P10253 5/20 0.53
CA9 Q16790 5/20 0.53
CA12 O43570 4/20 0.53
CASP1 P29466 3/20 0.53
CASP7 P55210 3/20 0.53
CA1 P00915 3/20 0.53
LMNA P02545 2/20 0.53
AKR1B1 P15121 2/20 0.53
MCL1 Q07820 2/20 0.53
MAOB P27338 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
UGT1A1 P22309 1/20 0.53
KDR P35968 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733054 0.82 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDHSD17B10GLA
SCHEMBL13058010 0.81 CSF1R (0.64) CSF1RALDH1A1KDM4EHPGDHSD17B10
SCHEMBL13406788 0.81 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10GLA
SCHEMBL19831190 0.81 CSF1R (0.52) CSF1RALDH1A1KDM4EHSD17B10CA9
SCHEMBL24097669 0.77 CSF1R (0.53) CSF1RALDH1A1HPGDGAACA9
SCHEMBL32670724 0.77 CA9 (0.46) CSF1RALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1530430 0.77 CSF1R (0.44) CSF1RALDH1A1KDM4ECA9CA12
SCHEMBL3331698 0.77 CA9 (0.46) CSF1RALDH1A1KDM4EHPGDHSD17B10
SCHEMBL10170879 0.77 CSF1R (0.59) CSF1RALDH1A1KDM4EHPGDHSD17B10
SCHEMBL18015271 0.74 CSF1R (0.51) CSF1RALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8137990-B2 Compositions for chemiluminescent detection of hydrogen peroxide LUMIGEN, INC. (US) 2012-03-20 US disclosed
US-8137990-B2 Compositions for chemiluminescent detection of hydrogen peroxide LUMIGEN, INC. (US) 2012-03-20 US disclosed
US-7704752-B2 Signalling compounds for use in methods of detecting hydrogen peroxide LUMIGEN, INC. (US) 2010-04-27 US disclosed
US-7704752-B2 Signalling compounds for use in methods of detecting hydrogen peroxide LUMIGEN, INC. (US) 2010-04-27 US disclosed
US-20100055800-A1 Compositions for Chemiluminescent Detection of Hydrogen Peroxide LUMIGEN, INC. (US) 2010-03-04 US disclosed
US-20100055800-A1 Compositions for Chemiluminescent Detection of Hydrogen Peroxide LUMIGEN, INC. (US) 2010-03-04 US disclosed
US-20080261318-A1 Signalling Compounds For Use In Methods Of Detecting Hydrogen Peroxide LUMIGEN, INC. (US) 2008-10-23 US disclosed
US-20080261318-A1 Signalling Compounds For Use In Methods Of Detecting Hydrogen Peroxide LUMIGEN, INC. (US) 2008-10-23 US disclosed
US-7390670-B2 Signalling compounds and methods for detecting hydrogen peroxide LUMIGEN, INC. (US) 2008-06-24 US disclosed
US-7390670-B2 Signalling compounds and methods for detecting hydrogen peroxide LUMIGEN, INC. (US) 2008-06-24 US disclosed