Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526383 | 0.78 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL29251525 | 0.76 | APEX1 (0.35) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL7336986 | 0.73 | KDM4E (0.45) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL27524563 | 0.69 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3507651 | 0.69 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL2032749 | 0.69 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL29251526 | 0.68 | APEX1 (0.40) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL29251520 | 0.67 | APEX1 (0.42) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL27628887 | 0.64 | MAPT (0.38) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL18180382 | 0.63 | KMT2A (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307094-A | ANTIHYPERTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1981-12-22 | — | — | US | disclosed |