Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524563 | 0.82 | CSNK2A2 (0.37) | KDM4EMAPTALDH1A1GAACSNK2A2 | |
| SCHEMBL6526383 | 0.77 | CSNK2A2 (0.37) | KDM4EMAPTALDH1A1GAACSNK2A2 | |
| SCHEMBL3507651 | 0.77 | CSNK2A2 (0.43) | KDM4EMAPTALDH1A1GAACSNK2A2 | |
| SCHEMBL2032749 | 0.77 | CSNK2A2 (0.43) | KDM4EMAPTALDH1A1GAACSNK2A2 | |
| SCHEMBL7344015 | 0.73 | CSNK2A2 (0.34) | MAPTALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27628887 | 0.71 | MAPT (0.38) | KDM4EMAPTALDH1A1GAACSNK2A2 | |
| SCHEMBL29251525 | 0.71 | APEX1 (0.35) | KDM4EMAPTALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL1729905 | 0.68 | KMT2A (0.38) | KDM4EMAPTALDH1A1GAACSNK2A2 | |
| SCHEMBL18180382 | 0.66 | KMT2A (0.45) | KDM4EGAAKMT2AUSP5CASP1 | |
| SCHEMBL11397353 | 0.65 | ALDH1A1 (0.41) | KDM4EMAPTALDH1A1GAACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307094-A | ANTIHYPERTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1981-12-22 | — | — | US | disclosed |