Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 20/20 | 0.77 |
| ▸ | PLG | P00747 | 15/20 | 0.77 |
| ▸ | KLKB1 | P03952 | 14/20 | 0.77 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.77 |
| ▸ | F2 | P00734 | 13/20 | 0.77 |
| ▸ | PLAT | P00750 | 12/20 | 0.77 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309463 | 0.87 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL30583187 | 0.87 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7344225 | 0.83 | PLAU (0.55) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7336833 | 0.81 | PLAU (0.88) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL5000845 | 0.78 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7344370 | 0.74 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7335930 | 0.72 | PLAU (0.78) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7336455 | 0.72 | PLAU (0.78) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7340321 | 0.71 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7339262 | 0.71 | PLAU (0.73) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |