Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340053 | 0.95 | SIGMAR1 (0.39) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7338860 | 0.94 | SIGMAR1 (0.37) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7345591 | 0.94 | SIGMAR1 (0.36) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7345518 | 0.93 | SIGMAR1 (0.38) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7343594 | 0.92 | SIGMAR1 (0.36) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7340239 | 0.91 | SIGMAR1 (0.37) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7778599 | 0.91 | SIGMAR1 (0.37) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7337033 | 0.90 | SIGMAR1 (0.39) | SIGMAR1AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7342217 | 0.88 | SIGMAR1 (0.37) | SIGMAR1MEN1KMT2AUSP2TP53 | |
| SCHEMBL7343781 | 0.86 | SIGMAR1 (0.35) | SIGMAR1MEN1KMT2AUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |