SCHEMBL7344290

SCHEMBL7344290

COc1ccc(C(=O)O)cc1OC1CCC(O)C1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA7 P43166 1/20 0.59
TPMT P51580 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
PDE4B Q07343 11/20 0.59
PDE4D Q08499 11/20 0.59
PDE4A P27815 9/20 0.59
PDE4C Q08493 9/20 0.59
TSHR P16473 2/20 0.51
MAPK14 Q16539 1/20 0.49
HTT P42858 2/20 0.49
CYP2D6 P10635 1/20 0.48
LMNA P02545 1/20 0.48
MAPK1 P28482 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7344303 1.00 CA12 (0.59) CA12CA1CA2CA4CA6
SCHEMBL7344294 1.00 CA12 (0.59) CA12CA1CA2CA4CA6
SCHEMBL2590117 0.94 CA12 (0.59) CA12CA1CA2CA4CA6
SCHEMBL28846183 0.90 PDE4B (0.70) CA12CA1CA2CA4CA6
SCHEMBL29670222 0.86 CA12 (0.63) CA12CA1CA2CA4CA6
SCHEMBL16517064 0.86 CA12 (0.63) CA12CA1CA2CA4CA6
SCHEMBL30009845 0.84 PDE4B (0.80) CA12CA1CA2CA4CA6
SCHEMBL1028427 0.84 PDE4B (0.80) CA12CA1CA2CA4CA6
SCHEMBL16516951 0.84 CA12 (0.69) CA12CA1CA2CA4CA6
SCHEMBL9005494 0.83 PDE4D (0.78) CA12CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996031476-A1 AROMATIC HYDROXYETHERS RHONE-POULENC RORER LIMITED (GB) 1996-10-10 WO disclosed