Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 7/20 | 0.47 |
| ▸ | F2 | P00734 | 8/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | CPN1 | P15169 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352341 | 1.00 | F7 (0.47) | F7F2ITGB3ITGA2BCPN1 | |
| SCHEMBL8504027 | 0.86 | F2 (0.43) | F7F2ITGB3ITGA2BTPSAB1 | |
| SCHEMBL7417189 | 0.86 | F2 (0.43) | F7F2ITGB3ITGA2BTPSAB1 | |
| SCHEMBL9263614 | 0.81 | KLK5 (0.40) | F7F2ITGB3ITGA2BCPN1 | |
| SCHEMBL9264866 | 0.79 | F2 (0.42) | F7F2ITGB3ITGA2BTPSAB1 | |
| SCHEMBL7344449 | 0.78 | ITGB3 (0.66) | F7F2ITGB3ITGA2B | |
| SCHEMBL7352353 | 0.78 | ITGB3 (0.66) | F7F2ITGB3ITGA2B | |
| SCHEMBL9264977 | 0.78 | F2 (0.41) | F7F2ITGB3ITGA2BCPN1 | |
| SCHEMBL6972937 | 0.77 | PARP1 (0.58) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL9440496 | 0.76 | ITGB3 (0.50) | F7F2ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344957-A | Amidinoiphenyl-substituted | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1993007867-A1 | SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |