Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269876 | 0.82 | ALDH1A1 (0.42) | MAPK1TSHRALDH1A1MAPTGPR35 | |
| SCHEMBL8903978 | 0.81 | ATM (0.38) | MAPK1TSHRALDH1A1MAPTVCAM1 | |
| SCHEMBL157744 | 0.74 | CYP3A4 (0.45) | MAPK1TSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL8194088 | 0.73 | SMN1; SMN2 (0.46) | TSHRALDH1A1MAPTNPSR1GPR35 | |
| SCHEMBL30389963 | 0.72 | CYP3A4 (0.43) | MAPK1TSHRALDH1A1MAPTVCAM1 | |
| SCHEMBL1998053 | 0.72 | CYP3A4 (0.43) | MAPK1TSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL6021382 | 0.72 | TSHR (0.53) | MAPK1TSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL7351325 | 0.70 | ALDH1A1 (0.38) | MAPK1TSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL7352678 | 0.70 | GRIN2D (0.46) | MAPK1TSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL7350652 | 0.70 | GRIN2D (0.38) | TSHRALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005337-A1 | USE OF GABA AND NMDA RECEPTOR LIGANDS FOR THE TREATMENT OF MIGRAINE HEADACHE | COCENSYS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |