Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965162 | 1.00 | EDNRA (0.58) | EDNRAEDNRB | |
| SCHEMBL6968356 | 0.86 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL6963755 | 0.84 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL27801659 | 0.78 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7017726 | 0.77 | EDNRA (0.56) | EDNRAEDNRB | |
| SCHEMBL6151283 | 0.76 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL27456776 | 0.76 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7133049 | 0.75 | SLC40A1 (0.45) | EDNRAEDNRB | |
| SCHEMBL10063369 | 0.74 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL4630728 | 0.74 | EDNRA (0.65) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819125-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031492-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-10-10 | — | — | WO | disclosed |