SCHEMBL7344630

SCHEMBL7344630

COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@H](C(=O)NCC(=O)N2CCOCC2)C(C)C)C(C)C)ccc1OC

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7409077 0.99 REN (0.80) REN
SCHEMBL6045149 0.93 REN (0.81) REN
Hydrochloric Acid SCHEMBL6045123 0.92 REN (0.82) REN
SCHEMBL7302206 0.90 REN (0.77) REN
Hydrochloric Acid SCHEMBL7304565 0.90 REN (0.78) REN
SCHEMBL1596156 0.89 REN (0.79) REN
SCHEMBL7307162 0.89 REN (0.99) REN
Hydrochloric Acid SCHEMBL7305412 0.88 REN (1.00) REN
SCHEMBL7348384 0.88 REN (0.78) REN
SCHEMBL7302135 0.88 REN (0.99) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678503-B1 Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities NOVARTIS AG (CH) 1999-09-01 EP claimed