Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 5/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.49 |
| ▸ | FAP | Q12884 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341602 | 0.89 | F2 (0.44) | F2PRSS1 | |
| SCHEMBL9074957 | 0.87 | F2 (0.61) | F2PRSS1DPP4DPP8DPP9 | |
| SCHEMBL9075661 | 0.86 | DPP4 (0.54) | F2PRSS1DPP4DPP8DPP9 | |
| SCHEMBL9075665 | 0.86 | DPP4 (0.54) | F2PRSS1DPP4DPP8DPP9 | |
| SCHEMBL9414137 | 0.86 | DPP4 (0.54) | F2PRSS1DPP4DPP8DPP9 | |
| SCHEMBL9076978 | 0.83 | DPP4 (0.53) | F2PRSS1DPP4DPP8DPP9 | |
| SCHEMBL7343548 | 0.82 | DPP4 (0.53) | F2DPP4DPP8DPP9DPP7 | |
| SCHEMBL7343558 | 0.82 | DPP4 (0.53) | F2DPP4DPP8DPP9DPP7 | |
| SCHEMBL9077049 | 0.81 | F2 (0.49) | F2PRSS1DPP4DPP8DPP9 | |
| SCHEMBL9077052 | 0.81 | F2 (0.49) | F2PRSS1DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0623595-A1 | Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |