Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | RXRA | P19793 | 1/20 | 0.72 |
| ▸ | RXRB | P28702 | 1/20 | 0.72 |
| ▸ | RXRG | P48443 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13447402 | 0.97 | RXRA (0.72) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL11936093 | 0.87 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL7331010 | 0.81 | RXRA (0.60) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL5123728 | 0.78 | RXRA (0.51) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL5130276 | 0.78 | HTT (0.49) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL11940789 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL8166642 | 0.77 | HTT (0.58) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL5131100 | 0.76 | HTT (0.47) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL13565505 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTNPSR1RXRARXRB | |
| SCHEMBL11935308 | 0.76 | HTT (0.56) | SMN1; SMN2HTTNPSR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598962-A1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-06-01 | — | — | EP | disclosed |
| US-5296493-A | Analgesics or antiischemics | NEUROSEARCH A/S (DK) | 1994-03-22 | — | — | US | disclosed |