Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346087 | 0.93 | ITGB3 (0.53) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7345488 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7347076 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7352179 | 0.87 | ITGB3 (0.68) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7354349 | 0.83 | ITGB3 (0.67) | ITGB3ITGA2B | |
| SCHEMBL7347405 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7357579 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BENPP2POLBALDH1A1 | |
| SCHEMBL6980785 | 0.82 | CA12 (0.59) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8906494 | 0.81 | CA1 (0.46) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7348197 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542708-B1 | Substituted beta-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2001-05-30 | — | — | EP | disclosed |
| US-5973003-A | TREATMENT OF THROMBOSIS, STROKE, MYOCARDIAL INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS | G. D. SEARLE & CO. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0614360-B1 | SUBSTITUTED BETA-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5344957-A | Amidinoiphenyl-substituted | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0542708-A1 | Substituted B-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |