Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 14/20 | 0.78 |
| ▸ | PLG | P00747 | 5/20 | 0.63 |
| ▸ | KLK1 | P06870 | 5/20 | 0.63 |
| ▸ | PLAT | P00750 | 4/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7340240 | 0.89 | PLAU (0.64) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7336792 | 0.88 | PLAU (1.00) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7336791 | 0.88 | PLAU (1.00) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7337316 | 0.81 | PLAU (0.72) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7337309 | 0.81 | PLAU (0.72) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7335165 | 0.81 | PLAU (0.52) | PLAUPLGKLK1PLATF12 | |
| SCHEMBL7342663 | 0.79 | PLAU (0.59) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7336960 | 0.79 | PLAU (0.58) | PLAUPLGKLK1PLATF2 | |
| Hydrochloric Acid SCHEMBL7336321 | 0.78 | PLAU (0.57) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7335620 | 0.77 | KDM4E (0.53) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |