Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 15/20 | 0.64 |
| ▸ | PLG | P00747 | 6/20 | 0.52 |
| ▸ | KLK1 | P06870 | 6/20 | 0.52 |
| ▸ | PLAT | P00750 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 5/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344842 | 0.89 | PLAU (0.78) | PLAUPLGKLK1PLATF2 | |
| Trifluoroacetic Acid SCHEMBL7336137 | 0.82 | PLAU (0.79) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7336791 | 0.79 | PLAU (1.00) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7336792 | 0.79 | PLAU (1.00) | PLAUPLGKLK1PLATF2 | |
| Trifluoroacetic Acid SCHEMBL7345645 | 0.78 | PLAU (0.59) | PLAUPLGKLK1PLATF2 | |
| SCHEMBL7340245 | 0.78 | PLAU (0.44) | PLAUPLGKLK1PLATF2 | |
| Trifluoroacetic Acid SCHEMBL7337450 | 0.76 | PLAU (0.55) | PLAUPLGKLK1PLATF2 | |
| Trifluoroacetic Acid SCHEMBL7342361 | 0.74 | PLAU (0.79) | PLAUPLGKLK1PLATF2 | |
| Trifluoroacetic Acid SCHEMBL7346166 | 0.74 | PLAU (0.66) | PLAUPLGKLK1PLATF2 | |
| Trifluoroacetic Acid SCHEMBL7335057 | 0.74 | ASIC3 (0.79) | PLAUPLGKLK1PLATF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |