SCHEMBL7344920

SCHEMBL7344920

N=C(N)c1ccc(CCc2ccc3c(c2)CCN(CC(=O)O)C3=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 1.00
ITGA2B P08514 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7025715 0.94 ITGB3 (0.88) ITGB3ITGA2B
SCHEMBL7343076 0.90 ITGB3 (0.82) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7032202 0.85 ITGB3 (0.74) ITGB3ITGA2B
SCHEMBL7333721 0.84 ITGB3 (1.00) ITGB3ITGA2B
SCHEMBL7332899 0.83 ITGB3 (1.00) ITGB3ITGA2B
SCHEMBL7345980 0.82 ITGB3 (1.00) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7029866 0.80 ITGB3 (0.89) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7025926 0.79 ITGB3 (0.89) ITGB3ITGA2B
SCHEMBL7797432 0.78 ITGB3 (0.63) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7035525 0.77 ITGB3 (0.89) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996022288-A1 GLYCOPROTEIN IIb/IIIa ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-07-25 WO disclosed