Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.58 |
| ▸ | YAP1 | P46937 | 3/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 3/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.49 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.49 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345107 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL7342880 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL7342873 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL21023244 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL11938562 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL7344934 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL7345113 | 1.00 | CACNA1B (0.58) | CACNA1BYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL7345875 | 0.94 | YAP1 (0.60) | CACNA1BYAP1REN | |
| SCHEMBL7339092 | 0.94 | YAP1 (0.60) | CACNA1BYAP1REN | |
| SCHEMBL7345873 | 0.94 | YAP1 (0.60) | CACNA1BYAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |