Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.65 |
| ▸ | OXTR | P30559 | 1/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344881 | 0.84 | AVPR1A (0.72) | AVPR2OXTRAVPR1A | |
| SCHEMBL7345982 | 0.82 | RAB9A (0.78) | — | |
| SCHEMBL7351740 | 0.82 | AVPR2 (0.94) | AVPR2OXTRAVPR1A | |
| SCHEMBL8562633 | 0.81 | AVPR2 (0.55) | AVPR2OXTRAVPR1A | |
| SCHEMBL3456488 | 0.81 | HPGD (0.83) | AVPR2OXTRAVPR1A | |
| SCHEMBL7347848 | 0.81 | RAB9A (0.72) | — | |
| SCHEMBL8712389 | 0.81 | AVPR2 (0.76) | AVPR2OXTRAVPR1A | |
| SCHEMBL7355637 | 0.81 | AVPR1A (0.77) | AVPR2OXTRAVPR1A | |
| SCHEMBL7359695 | 0.80 | AVPR1A (0.67) | AVPR1A | |
| SCHEMBL7351861 | 0.79 | AVPR2 (0.81) | AVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |