Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 13/20 | 1.00 |
| ▸ | PLG | P00747 | 13/20 | 0.80 |
| ▸ | KLK1 | P06870 | 11/20 | 0.80 |
| ▸ | PLAT | P00750 | 8/20 | 0.80 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.80 |
| ▸ | F2 | P00734 | 4/20 | 0.80 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | KLK6 | Q92876 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339552 | 0.89 | PLAU (0.81) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL7341506 | 0.89 | PLAU (0.81) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL4320529 | 0.89 | PLAU (1.00) | PLAUPLGKLK1PLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7336462 | 0.84 | PLAU (0.90) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL6433868 | 0.83 | PLAU (0.70) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL6439559 | 0.81 | PLAU (0.86) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL7358945 | 0.80 | PLAU (0.67) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL7358951 | 0.80 | PLAU (0.67) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL6436054 | 0.77 | PLAU (1.00) | PLAUPLGKLK1PLATPRSS1 | |
| SCHEMBL6439587 | 0.75 | PLAU (0.60) | PLAUPLGKLK1PLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |