Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345211 | 1.00 | CYP19A1 (0.59) | CYP19A1BACE1MAPTNPSR1RAB9A | |
| SCHEMBL29809086 | 0.82 | CYP19A1 (0.65) | CYP19A1BACE1MAPTRAB9AALDH1A1 | |
| SCHEMBL11307663 | 0.82 | CYP19A1 (0.65) | CYP19A1BACE1MAPTRAB9AALDH1A1 | |
| SCHEMBL11307656 | 0.82 | CYP19A1 (0.65) | CYP19A1BACE1MAPTRAB9AALDH1A1 | |
| SCHEMBL1138832 | 0.82 | BACE1 (0.59) | CYP19A1BACE1MAPTLMNAMEN1 | |
| SCHEMBL521421 | 0.81 | TSHR (0.67) | MAPTNPSR1RAB9AALDH1A1ATM | |
| SCHEMBL521422 | 0.81 | TSHR (0.67) | MAPTNPSR1RAB9AALDH1A1ATM | |
| SCHEMBL20493432 | 0.80 | ERN1 (0.54) | CYP19A1MAPTRAB9AALDH1A1MAOB | |
| SCHEMBL5252570 | 0.80 | RELA (0.60) | MAPTRAB9AALDH1A1MAOBLMNA | |
| SCHEMBL28460574 | 0.80 | CYP19A1 (0.76) | CYP19A1BACE1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |