Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335834 | 0.95 | MME (0.50) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7338611 | 0.92 | MMP9 (0.47) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7340102 | 0.92 | MMP9 (0.47) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7338052 | 0.91 | PPARG (0.49) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7338315 | 0.90 | PPARG (0.52) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7344073 | 0.89 | PPARG (0.62) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7346125 | 0.89 | MME (0.52) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7339870 | 0.89 | MME (0.49) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7341933 | 0.88 | PPARG (0.50) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7337025 | 0.88 | KLKB1 (0.52) | PPARGMMP9MMP8MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |