Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335837 | 0.95 | MME (0.56) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7338614 | 0.91 | IL1RN (0.51) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7340103 | 0.91 | IL1RN (0.51) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7338054 | 0.90 | IL1RN (0.53) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7338318 | 0.89 | IL1RN (0.56) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7346128 | 0.88 | MME (0.58) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7339872 | 0.88 | IL1RN (0.55) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7344077 | 0.88 | PPARG (0.60) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7341943 | 0.87 | CTSS (0.53) | IL1RNERAP2ERAP1PTPN1MME | |
| SCHEMBL7338671 | 0.87 | IL1RN (0.53) | IL1RNERAP2ERAP1PTPN1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |