Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | PREP | P48147 | 4/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9076507 | 0.99 | KEAP1 (0.50) | KEAP1NFE2L2PREPPRCPTPSAB1 | |
| Hydrochloric Acid SCHEMBL9076513 | 0.99 | KEAP1 (0.50) | KEAP1NFE2L2PREPPRCPTPSAB1 | |
| SCHEMBL7341069 | 0.86 | KEAP1 (0.49) | KEAP1NFE2L2PREPPRCPF2 | |
| SCHEMBL7341061 | 0.86 | KEAP1 (0.49) | KEAP1NFE2L2PREPPRCPF2 | |
| Hydrochloric Acid SCHEMBL11269585 | 0.73 | DPP8 (0.48) | KEAP1NFE2L2PREPPRCPTPSAB1 | |
| SCHEMBL8298475 | 0.72 | NPC1 (0.42) | HTTCPB1GAA | |
| SCHEMBL8298476 | 0.72 | NPC1 (0.42) | HTTCPB1GAA | |
| SCHEMBL18254066 | 0.71 | HTT (0.81) | KEAP1NFE2L2DPP8DPP7HTT | |
| SCHEMBL16392606 | 0.71 | PREP (0.61) | KEAP1NFE2L2PREPPRCPDPP8 | |
| SCHEMBL21567094 | 0.71 | PREP (0.55) | KEAP1NFE2L2PREPTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |