Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | METAP1 | P53582 | 3/20 | 0.51 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622270 | 0.86 | CYP24A1 (0.61) | CYP24A1CYP26A1ACHEMETAP1CYP27A1 | |
| SCHEMBL7308911 | 0.83 | METAP1 (0.53) | CYP24A1CYP26A1ACHEMETAP1CYP27A1 | |
| SCHEMBL7344655 | 0.82 | METAP1 (0.45) | ACHEMETAP1CYP19A1 | |
| Hydrochloric Acid SCHEMBL9426254 | 0.82 | METAP1 (0.54) | CYP24A1CYP26A1ACHEMETAP1CYP27A1 | |
| SCHEMBL4623999 | 0.81 | CYP24A1 (0.58) | CYP24A1CYP26A1ACHEMETAP1CYP27A1 | |
| SCHEMBL4621871 | 0.80 | CYP24A1 (0.68) | CYP24A1CYP26A1ACHEMETAP1CYP27A1 | |
| SCHEMBL7590283 | 0.79 | METAP1 (0.78) | CYP24A1CYP26A1METAP1CYP27A1CYP19A1 | |
| SCHEMBL8012038 | 0.79 | METAP1 (0.78) | CYP24A1CYP26A1METAP1CYP27A1CYP19A1 | |
| SCHEMBL7345539 | 0.79 | METAP1 (0.46) | ACHEMETAP1CYP19A1 | |
| SCHEMBL9855296 | 0.79 | CYP24A1 (0.63) | CYP24A1CYP26A1ACHEMETAP1CYP27A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581677-B1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | JOUVEINAL INST RECH (FR) | 1997-01-08 | — | — | EP | disclosed |
| US-5326784-A | Psychological and gastrointestinal disorders | INSTITUT DE RECHERCHE JOUVEINAL (FR) | 1994-07-05 | — | — | US | disclosed |
| EP-0581677-A1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1994-02-02 | — | — | EP | disclosed |