Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345529 | 1.00 | PSMB5 (0.55) | PSMB5LPAR1LPAR3ENPP2IL1RN | |
| SCHEMBL7343222 | 0.93 | IL1RN (0.55) | PSMB5IL1RNERAP2ERAP1REN | |
| SCHEMBL7343224 | 0.93 | IL1RN (0.55) | PSMB5IL1RNERAP2ERAP1REN | |
| SCHEMBL7344233 | 0.90 | IL1RN (0.56) | PSMB5IL1RNERAP2ERAP1REN | |
| SCHEMBL7344241 | 0.90 | IL1RN (0.56) | PSMB5IL1RNERAP2ERAP1REN | |
| SCHEMBL7337118 | 0.88 | REN (0.52) | IL1RNERAP2ERAP1REN | |
| SCHEMBL7337124 | 0.88 | REN (0.52) | IL1RNERAP2ERAP1REN | |
| SCHEMBL7348608 | 0.88 | REN (0.51) | IL1RNERAP2ERAP1RENYAP1 | |
| SCHEMBL7348604 | 0.88 | REN (0.51) | IL1RNERAP2ERAP1RENYAP1 | |
| SCHEMBL7337332 | 0.87 | REN (0.51) | IL1RNERAP2ERAP1RENYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |