Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138147 | 0.79 | HSD17B10 (0.50) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL16118877 | 0.77 | KMT2A (0.36) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL6320482 | 0.77 | KDM4E (0.54) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19148315 | 0.77 | HSD17B10 (0.48) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL12226477 | 0.77 | KMT2A (0.40) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL1259865 | 0.75 | — | — | |
| SCHEMBL1259117 | 0.75 | — | — | |
| SCHEMBL2213971 | 0.74 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13671234 | 0.74 | KMT2A (0.38) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL1258251 | 0.73 | GAA (0.56) | NPC1ALDH1A1CYP1A2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |