Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.55 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342507 | 0.89 | LTA4H (0.52) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL7335830 | 0.84 | CACNA1B (0.52) | PSMB5GPR34PSMB1 | |
| SCHEMBL7345070 | 0.83 | HDAC8 (0.60) | LTA4HIL1RNERAP2ERAP1HDAC8 | |
| SCHEMBL7348742 | 0.83 | LTA4H (0.59) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL7336536 | 0.83 | LTA4H (0.59) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL7342789 | 0.83 | LTA4H (0.58) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL7336924 | 0.82 | PSMB5 (0.51) | PSMB5GPR34PSMB1MMEACE | |
| SCHEMBL7344263 | 0.82 | MEN1 (0.55) | PSMB5PSMB1MMEACECPA1 | |
| SCHEMBL7340297 | 0.82 | LTA4H (0.57) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL7336784 | 0.82 | LTA4H (0.57) | MMEACECPA1ACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |