Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 11/20 | 0.59 |
| ▸ | F2 | P00734 | 5/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | PLG | P00747 | 4/20 | 0.54 |
| ▸ | KLK1 | P06870 | 3/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342926 | 0.88 | PLAU (0.74) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7333611 | 0.86 | PLAU (0.56) | PLAUF2PRSS1PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL7333551 | 0.82 | PLAU (0.44) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7336431 | 0.82 | PLAU (0.47) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7337450 | 0.81 | PLAU (0.55) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7342361 | 0.80 | PLAU (0.79) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7336137 | 0.80 | PLAU (0.79) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7335057 | 0.80 | ASIC3 (0.79) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7337115 | 0.78 | PLAU (0.80) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7334922 | 0.78 | PLAU (0.85) | PLAUF2PRSS1PLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |