Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033162 | 0.95 | PRCP (0.61) | PRCPTDP1EPHX1MAOAMAOB | |
| SCHEMBL13767206 | 0.94 | PRCP (0.56) | PRCPTDP1EPHX1MEN1GAA | |
| SCHEMBL15665243 | 0.87 | PRCP (0.61) | PRCPTLR2HTR2CFPR3FPR2 | |
| SCHEMBL15665421 | 0.87 | PRCP (0.61) | PRCPTLR2HTR2CFPR3FPR2 | |
| SCHEMBL3957702 | 0.81 | MEN1 (0.44) | PRCPTDP1EPHX1MEN1GAA | |
| SCHEMBL27512384 | 0.81 | PRCP (0.43) | PRCPTDP1EPHX1MAOAMAOB | |
| SCHEMBL7299117 | 0.80 | PRCP (0.43) | PRCPEPHX1GAATLR2HTR2C | |
| SCHEMBL373560 | 0.80 | PRCP (0.43) | PRCPEPHX1GAATLR2HTR2C | |
| SCHEMBL28232408 | 0.80 | PRCP (0.43) | PRCPEPHX1GAATLR2HTR2C | |
| SCHEMBL23762418 | 0.80 | PRCP (0.97) | PRCPEPHX1TLR2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |