Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392291 | 0.83 | ADAM17 (0.42) | MEN1KMT2AGAAADAM17PRCP | |
| SCHEMBL13997573 | 0.82 | DPP7 (0.47) | MEN1KMT2APRCPHDAC1HDAC6 | |
| SCHEMBL7345915 | 0.81 | PRCP (0.64) | MEN1KMT2AGAAPRCPCA1 | |
| SCHEMBL13767206 | 0.81 | PRCP (0.56) | MEN1KMT2AGAAPRCPDPP7 | |
| SCHEMBL5033162 | 0.77 | PRCP (0.61) | MEN1KMT2AGAAPRCPCA1 | |
| SCHEMBL23039353 | 0.77 | PRCP (0.48) | MEN1KMT2APRCPHDAC1HDAC6 | |
| SCHEMBL23039355 | 0.77 | PRCP (0.48) | MEN1KMT2APRCPHDAC1HDAC6 | |
| SCHEMBL22127949 | 0.77 | PRCP (0.48) | MEN1KMT2APRCPHDAC1HDAC6 | |
| SCHEMBL23039354 | 0.77 | PRCP (0.48) | MEN1KMT2APRCPHDAC1HDAC6 | |
| SCHEMBL4887762 | 0.76 | MEN1 (0.61) | MEN1KMT2AGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866291-B1 | ANTIBACTERIAL AMIDE MACROCYCLES VI | AICURIS GMBH & CO KG (DE) | 2009-07-15 | — | — | EP | disclosed |
| US-20080300231-A1 | Antibacterial amide macrocycles VI | BAYER HEALTHCARE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300231-A1 | Antibacterial amide macrocycles VI | BAYER HEALTHCARE AG (DE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300231-A1 | Antibacterial amide macrocycles VI | AADAC, AAAS, NOD2 | MEN1 1894/4885KMT2A 3331/4885GAA 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.