Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346000 | 0.91 | PDE4D (0.44) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7348607 | 0.89 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7369626 | 0.87 | PDE4D (0.44) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7341082 | 0.86 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7344138 | 0.81 | GAA (0.42) | TP53GAABRD4 | |
| SCHEMBL7340419 | 0.81 | TP53 (0.51) | TP53GAABRD4 | |
| SCHEMBL7341146 | 0.80 | BRD4 (0.49) | TP53GAABRD4 | |
| SCHEMBL7366621 | 0.79 | TP53 (0.41) | TP53GAABRD4 | |
| SCHEMBL7342173 | 0.78 | AVPR2 (0.43) | TP53GAABRD4 | |
| SCHEMBL7342198 | 0.78 | RXFP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |