Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345937 | 0.89 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7346000 | 0.88 | PDE4D (0.44) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7369626 | 0.85 | PDE4D (0.44) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7339219 | 0.85 | KCNMA1 (0.48) | TOP2AKCNMA1TP53GAAMAPT | |
| SCHEMBL7341082 | 0.84 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL7337765 | 0.78 | KCNMA1 (0.44) | KCNMA1TP53GAAMAPTKMT2A | |
| SCHEMBL7338015 | 0.76 | KCNMA1 (0.42) | KCNMA1TP53GAAMAPTKMT2A | |
| SCHEMBL7372454 | 0.75 | KCNMA1 (0.48) | KCNMA1TP53GAAMAPTKMT2A | |
| SCHEMBL7512858 | 0.75 | ALDH1A1 (0.50) | KCNMA1TP53GAAMAPTKMT2A | |
| SCHEMBL7342198 | 0.75 | RXFP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |