SCHEMBL7346172

SCHEMBL7346172

O=C(O)C(Cc1ccccc1)Cc1ccncc1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.77
CPA1 P15085 7/20 0.61
CPA3 P15088 3/20 0.61
FOLH1 Q04609 2/20 0.61
CPB1 P15086 1/20 0.61
CPB2 Q96IY4 1/20 0.61
ANPEP P15144 1/20 0.58
ERAP2 Q6P179 1/20 0.58
ERAP1 Q9NZ08 1/20 0.58
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
ALDH1A1 P00352 1/20 0.54
CYP3A4 P08684 1/20 0.54
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
SLC6A3 Q01959 1/20 0.53
MME P08473 1/20 0.53
NAALAD2 Q9Y3Q0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4664822 0.88 CYP1A2 (1.00) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL27291058 0.86 CYP1A2 (0.95) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL22115491 0.86 CYP1A2 (0.95) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL9875948 0.86 CYP1A2 (0.95) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL7048054 0.83 FOLH1 (0.70) CYP1A2CPA3FOLH1
SCHEMBL20366129 0.83 CPA1 (0.70) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL7278126 0.82 ALDH1A1 (0.62) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL5057989 0.82 ERAP2 (0.62) CYP1A2CPA1CPA3FOLH1ANPEP
SCHEMBL7439697 0.81 CYP1A2 (0.86) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL9622038 0.81 CYP1A2 (0.86) CYP1A2CPA1CPA3FOLH1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991009838-A1 NEW AMIDES AKTIEBOLAGET ASTRA (SE) 1991-07-11 WO disclosed
EP-0353211-A1 New compounds Aktiebolaget Hässle (SE) 1990-01-31 EP disclosed