Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914175 | 0.96 | GBA1 (0.40) | GBA1SLC18A3SIGMAR1CCR3USP30 | |
| SCHEMBL3925509 | 0.92 | GBA1 (0.42) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL3955954 | 0.84 | GBA1 (0.62) | GBA1CCR3 | |
| SCHEMBL10966387 | 0.82 | EED (0.53) | GBA1 | |
| SCHEMBL19283190 | 0.81 | GBA1 (0.35) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL19639047 | 0.81 | ACHE (0.47) | SIGMAR1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL27312409 | 0.78 | PTGS1 (0.41) | GBA1SLC18A3 | |
| SCHEMBL6667025 | 0.76 | HDAC6 (0.48) | SIGMAR1 | |
| SCHEMBL28193252 | 0.76 | GBA1 (0.43) | GBA1SLC18A3SIGMAR1CCR3PRMT3 | |
| SCHEMBL7403015 | 0.75 | GBA1 (0.41) | GBA1SLC18A3SIGMAR1CCR3PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | claimed |
| CN-1089935-A | Octadecyloxy phenyl acid derivative, its preparation method and optical isomer separation method thereof | HISAMITSU PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | CN | disclosed |
| CN-1069484-A | Octadecyloxy phenyl acid derivative, its preparation method and optical isomer separation method thereof | HISAMITSU PHARMACEUTICAL CO (JP) | 1993-03-03 | — | — | CN | disclosed |