Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340750 | 0.90 | MEN1 (0.45) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7350850 | 0.89 | CNR2 (0.48) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7346787 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7342400 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7340688 | 0.89 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7340527 | 0.89 | CA12 (0.49) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7339248 | 0.89 | KDM4E (0.47) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7343295 | 0.87 | RNF4 (0.46) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7342493 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRHDAC1HDAC8 | |
| SCHEMBL7347840 | 0.81 | MAPT (0.50) | ALDH1A1KDM4ETSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |