Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MGAM | O43451 | 3/20 | 0.52 |
| ▸ | SI | P14410 | 3/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638270 | 0.86 | GAA (0.62) | GAAKDM4EALDH1A1CA12CA9 | |
| SCHEMBL29854772 | 0.84 | CA12 (0.66) | GAAKDM4EALDH1A1CA12CA9 | |
| SCHEMBL831768 | 0.84 | CA12 (0.66) | GAAKDM4EALDH1A1CA12CA9 | |
| SCHEMBL2266790 | 0.81 | CA12 (0.58) | KDM4EALDH1A1CA12CA9MAPT | |
| SCHEMBL9528397 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1CA12CA9MAPT | |
| SCHEMBL15842594 | 0.79 | CYP2C9 (0.57) | GAAKDM4EALDH1A1CA12CA9 | |
| SCHEMBL1230426 | 0.77 | GAA (1.00) | GAAKDM4EALDH1A1MAPTMGAM | |
| SCHEMBL94134 | 0.77 | GAA (0.69) | GAAKDM4EALDH1A1MAPTMGAM | |
| SCHEMBL17760847 | 0.76 | CA12 (0.60) | GAAKDM4EALDH1A1CA12CA9 | |
| SCHEMBL22193185 | 0.76 | POLB (0.62) | GAAKDM4EALDH1A1MAPTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542708-B1 | Substituted beta-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2001-05-30 | — | — | EP | disclosed |
| US-5973003-A | TREATMENT OF THROMBOSIS, STROKE, MYOCARDIAL INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS | G. D. SEARLE & CO. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5703125-A | MELT BLEND OF SOAP, SURFACTANT AND SOLVENT | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0614360-B1 | SUBSTITUTED BETA-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0614360-A1 | SUBSTITUTED -g(b)-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. | SEARLE & CO (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5344957-A | Amidinoiphenyl-substituted | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0542708-A1 | Substituted B-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993007867-A1 | SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |