SCHEMBL94134

SCHEMBL94134

Cc1c(N)c2ccccc2oc1=O

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 16/20 0.69
KDM4E B2RXH2 8/20 0.69
ALDH1A1 P00352 5/20 0.69
MGAM O43451 5/20 0.60
SI P14410 5/20 0.60
MGAM2 Q2M2H8 5/20 0.60
MAPT P10636 4/20 0.57
LMNA P02545 2/20 0.56
POLB P06746 2/20 0.55
HSD17B10 Q99714 4/20 0.53
HPGD P15428 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
USP2 O75604 1/20 0.50
MAPK1 P28482 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL472754 0.92 POLB (0.60) GAAKDM4EALDH1A1MGAMSI
SCHEMBL29515065 0.85 GAA (0.69) GAAKDM4EALDH1A1MGAMSI
SCHEMBL565925 0.85 GAA (0.69) GAAKDM4EALDH1A1MGAMSI
SCHEMBL2450078 0.84 KDM4E (0.71) GAAKDM4EALDH1A1MAPTHSD17B10
Bromide SCHEMBL25420644 0.83 GAA (0.67) GAAKDM4EALDH1A1MGAMSI
Hydrochloric Acid SCHEMBL29609753 0.83 GAA (0.67) GAAKDM4EALDH1A1MGAMSI
SCHEMBL1230426 0.82 GAA (1.00) GAAKDM4EALDH1A1MGAMSI
SCHEMBL6845346 0.79 ERAP1 (0.49) GAAKDM4EALDH1A1MGAMSI
Acetic Acid SCHEMBL4004465 0.78 GAA (0.59) GAAKDM4EALDH1A1MGAMSI
SCHEMBL6810405 0.77 GAA (0.69) GAAKDM4EALDH1A1MGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521422-B1 SUBSTANTIALLY ANIMAL PROTEIN-FREE RECOMBINAT FURIN AND METHODS FOR PRODUCING SAME TAKEDA PHARMACEUTICALS CO (JP) 2021-10-06 EP claimed
EP-3174953-B1 ENVIRONMENTALLY RESPONSIVE CHROMATIC LUMINESCENT COMPOSITIONS WITH IMPROVED HAND BAMBU VAULT LLC (US) 2020-09-02 EP claimed
EP-2240578-B1 SUBSTANTIALLY ANIMAL PROTEIN-FREE RECOMBINANT FURIN AND METHODS FOR PRODUCING SAME Baxalta GmbH (CH) 2019-03-20 EP claimed
EP-3174953-A1 ENVIRONMENTALLY RESPONSIVE CHROMIC LUMINESCENT MATERIALS WITH IMPROVED HAND Performance Indicator, LLC (US) 2017-06-07 EP claimed
CN-104303059-B Method for detecting intracellular infectious agents in sperm cells 瓦西利奥斯·齐列瓦可斯 2016-08-17 CN claimed
EP-2313785-B1 A METHOD AND ASSEMBLY FOR MEASURING THROMBIN GENERATION IN PLASMA SYNAPSE BV (NL) 2016-02-17 EP claimed
US-20160032182-A1 ENVIRONMENTALLY RESPONSIVE CHROMIC LUMINESCENT MATERIALS WITH IMPROVED HAND PERFORMANCE INDICATOR, LLC 2016-02-04 US claimed
WO-2016019100-A1 ENVIRONMENTALLY RESPONSIVE CHROMIC LUMINESCENT MATERIALS WITH IMPROVED HAND PERFORMANCE INDICATOR, LLC (US) 2016-02-04 WO claimed
US-9206241-B2 Modified prokaryotic ubiquitin-like protein and methods of use thereof NEW YORK UNIVERSITY (US) 2015-12-08 US claimed
US-9115382-B2 Kit for detection of hemolytic Streptococcus Mosher, Leroy E. (US) 2015-08-25 US claimed
EP-1330471-A1 LABELED PEPTIDES, AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION THE SCRIPPS RESEARCH INSTITUTE (US) 2003-07-30 EP claimed
US-20030118998-A1 Nucleic acid amplification QIAGEN GMBH (DE) 2003-06-26 US claimed
EP-1301473-A2 LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION The Scripps Research Institute (US) 2003-04-16 EP claimed
US-20020159952-A1 Novel acoustically active drug delivery systems BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. 2002-10-31 US claimed
US-20020055133-A1 Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation SCRIPPS RESEARCH INSTITUTE, THE 2002-05-09 US claimed
EP-0981333-A4 NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS IMARX PHARMACEUTICAL CORP (US) 2002-04-24 EP claimed
WO-2002028890-A1 LABELED PEPTIDES, AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION THE SCRIPPS RESEARCH INSTITUTE (US) 2002-04-11 WO claimed
WO-2002008245-A2 LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION THE SCRIPPS RESEARCH INSTITUTE (US) 2002-01-31 WO claimed
EP-0981333-A1 NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS IMARX PHARMACEUTICAL CORP. (US) 2000-03-01 EP claimed
WO-1998051284-A1 NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS IMARX PHARMACEUTICAL CORP. (US) 1998-11-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020159952-A1 Novel acoustically active drug delivery systems AURKA, AURKC, MTDH GAA 2046/4885KDM4E 4328/4885ALDH1A1 2848/4885
US-20020055133-A1 Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation ARHGEF1, RHOC, CIT GAA 2047/4885KDM4E 4613/4885ALDH1A1 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.