Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Desmethylvenlafaxine SCHEMBL5439972 | 1.00 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| N-Desmethylvenlafaxine SCHEMBL5435875 | 1.00 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL14135126 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL12645995 | 0.84 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL12187989 | 0.84 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL12165438 | 0.84 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL13657720 | 0.84 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL902641 | 0.84 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL16675664 | 0.83 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL5379416 | 0.83 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119452086-A | GAPMER antisense oligonucleotides with modified backbone chemistry | 奎里斯公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119185558-A | Methods and compositions for treating sleep apnea | 布里格姆妇女医院 | 2024-12-27 | — | — | CN | claimed |
| CN-111840300-B | Pharmaceutical composition for treating mental disorder and pain associated with nerve injury and use thereof | 香港城市大学 | 2024-03-12 | — | — | CN | claimed |
| CN-115884959-A | Biologically active phenolate ion complexes | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114994198-B | Method for simultaneously and quantitatively detecting 78 neuropsychiatric drugs by liquid chromatography-mass spectrometry | 上海市精神卫生中心（上海市心理咨询培训中心） | 2023-02-28 | — | — | CN | claimed |
| CN-114081867-A | Method for improving drug loading capacity of microspheres | 中国药科大学 | 2022-02-25 | — | — | CN | claimed |
| US-20070117870-A1 | Enantiomers of N-Desmethyl venlafaxine | WYETH (US) | 2007-05-24 | — | — | US | claimed |
| US-20060205821-A1 | Enantiomers of N-desmethyl venlafaxine | WYETH (US) | 2006-09-14 | — | — | US | claimed |
| US-20050267219-A1 | Enantiomers of N-desmethyl venlafaxine | WYETH (US) | 2005-12-01 | — | — | US | claimed |
| US-20040180966-A1 | Enantiomers of N-desmethyl venlafaxine | WYETH | 2004-09-16 | — | — | US | claimed |
| US-20030203972-A1 | Enantiomers of N-desmethyl venlafaxine | WYETH (US) | 2003-10-30 | — | — | US | claimed |
| US-20020165284-A1 | Enantiomers of N-desmethyl venlafaxine | WYETH | 2002-11-07 | — | — | US | claimed |
| US-20020035158-A1 | Enantiomers of N-desmethyl venlafaxine | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-21 | — | — | US | claimed |
| WO-2000076956-A2 | ENANTIOMERS OF N-DESMETHYL VENLAFAXINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-21 | — | — | WO | claimed |
| EP-0112669-B1 | PHENETHYLAMINE DERIVATIVES AND INTERMEDIATES THEREFOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-07-29 | — | — | EP | claimed |
| US-4535186-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS; VENLAFAXINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-08-13 | — | — | US | claimed |
| EP-0112669-A2 | Phenethylamine derivatives and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-07-04 | — | — | EP | claimed |
| CN-223581924-U | Venlafaxine and desmethylvenlafaxine blood concentration detection kit | 杭州和合医学检验实验室有限公司 | 2025-11-21 | — | — | CN | disclosed |
| US-4535186-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS; VENLAFAXINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0112669-A2 | Phenethylamine derivatives and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180966-A1 | Enantiomers of N-desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
| US-20060205821-A1 | Enantiomers of N-desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
| US-20030203972-A1 | Enantiomers of N-desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
| US-20020165284-A1 | Enantiomers of N-desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
| US-20050267219-A1 | Enantiomers of N-desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
| US-20020035158-A1 | Enantiomers of N-desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
| US-20070117870-A1 | Enantiomers of N-Desmethyl venlafaxine | SLC6A2, SLC6A3, SLC6A4 | SLC6A2 1/4885SLC6A4 3/4885SLC6A3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.