SCHEMBL734658

SCHEMBL734658

CC(=O)NCCc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
F13A1 P00488 1/20 1.00
SMN1; SMN2 Q16637 2/20 0.66
MAPT P10636 2/20 0.66
ALDH1A1 P00352 1/20 0.66
LMNA P02545 1/20 0.66
HPGD P15428 1/20 0.66
PTGS1 P23219 1/20 0.66
BLM P54132 1/20 0.66
HIF1A Q16665 1/20 0.66
HSD17B10 Q99714 1/20 0.66
TMEM97 Q5BJF2 1/20 0.59
SIGMAR1 Q99720 1/20 0.59
ESRRB O95718 3/20 0.57
ESRRG P62508 3/20 0.57
NPC1 O15118 1/20 0.56
CYP1A2 P05177 1/20 0.56
GAA P10253 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11713261 0.94 KDM4E (0.89) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL10592850 0.92 KDM4E (0.84) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL2167338 0.89 KDM4E (0.79) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL5707308 0.87 KDM4E (0.77) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL15358690 0.85 KDM4E (0.73) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL2093513 0.84 KDM4E (0.72) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL6845396 0.84 KDM4E (0.72) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL661278 0.84 KDM4E (0.72) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL11553305 0.84 KDM4E (0.72) KDM4EF13A1SMN1; SMN2MAPTALDH1A1
SCHEMBL5987671 0.84 KDM4E (0.72) KDM4EF13A1SMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613154-B Three-dimensional super-bright DTY fiber and production process thereof 浙江恒百华化纤有限公司 2024-06-07 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-116448932-A Analysis method for chemical components of periplaneta americana extract CII-3 大理大学 2023-07-18 CN claimed
CN-115613154-A Three-dimensional super-bright DTY fiber and production process thereof 浙江恒百华化纤有限公司 2023-01-17 CN claimed
CN-120375935-A Metabolic marker for predicting curative effect and prognosis of primary liver cancer and application thereof 华中科技大学同济医学院附属协和医院 2025-07-25 CN disclosed
CN-119816482-A Tyramide and tyramide analogue conjugates and their use for biological target staining procedures 生命技术公司 2025-04-11 CN disclosed
US-12174193-B2 Agents and methods for predicting response to therapy EPIAXIS THERAPEUTICS PTY LTD (AU) 2024-12-24 US disclosed
WO-2024246905-A1 ENZYMES, POLYNUCLEOTIDES ENCODING SAME, AND METHODS OF USING SAME FOR PRODUCING MESCALINE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-12-05 WO disclosed
CN-115613154-B Three-dimensional super-bright DTY fiber and production process thereof 浙江恒百华化纤有限公司 2024-06-07 CN disclosed
CN-111936857-B Reagents and methods for predicting response to therapy 艾比克斯治疗私人有限公司 2024-04-16 CN disclosed
CN-116448932-A Analysis method for chemical components of periplaneta americana extract CII-3 大理大学 2023-07-18 CN disclosed
CN-115613154-A Three-dimensional super-bright DTY fiber and production process thereof 浙江恒百华化纤有限公司 2023-01-17 CN disclosed
US-5110914-A Ion exchanging UNIVERSITY OF MIAMI (US) 1992-05-05 US disclosed
US-5086167-A Ion exchanging with a ligand/matrix using a combination of pi-electron and electrostatic interaction of the ligand and ionic amino acids UNIVERSITY OF MIAMI (US) 1992-02-04 US disclosed
EP-0371746-A2 Method of separating proteins UNIVERSITY OF MIAMI (US) 1990-06-06 EP disclosed
EP-0004011-B1 PHENOXYALKYLCARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Roche Diagnostics GmbH (DE) 1981-04-01 EP disclosed
US-4258058-A Phenoxyalkylcarboxylic acid compounds and thrombocyte-aggregation inhibition BOEHRINGER MANNHEIM GMBH (DE) 1981-03-24 US disclosed
EP-0004011-A1 Phenoxyalkylcarboxylic-acid derivatives, process for their preparation and medicaments containing them Roche Diagnostics GmbH (DE) 1979-09-19 EP disclosed
US-4153728-A ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS, ANTICOAGULANTS BOEHRINGER MANNHEIM GMBH (DE) 1979-05-08 US disclosed
US-4151303-A Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions BOEHRINGER MANNHEIM GMBH (DE) 1979-04-24 US disclosed