Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.89 |
| ▸ | F13A1 | P00488 | 1/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | ESRRB | O95718 | 3/20 | 0.53 |
| ▸ | ESRRG | P62508 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734658 | 0.94 | KDM4E (1.00) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10592850 | 0.87 | KDM4E (0.84) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10066080 | 0.86 | KDM4E (0.66) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2167338 | 0.84 | KDM4E (0.79) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5707308 | 0.82 | KDM4E (0.77) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5437522 | 0.81 | KDM4E (0.59) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL15358690 | 0.80 | KDM4E (0.73) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11553305 | 0.79 | KDM4E (0.72) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL661278 | 0.79 | KDM4E (0.72) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2093513 | 0.79 | KDM4E (0.72) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |