⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351338 | 1.00 | — | — | |
| SCHEMBL107504 | 1.00 | — | — | |
| Cyclohexene SCHEMBL8175251 | 0.95 | — | — | |
| SCHEMBL14612282 | 0.92 | — | — | |
| SCHEMBL1071594 | 0.92 | — | — | |
| Bicarbonate SCHEMBL5180989 | 0.90 | POLB (0.31) | — | |
| SCHEMBL25161927 | 0.89 | — | — | |
| SCHEMBL1535243 | 0.89 | TSHR (0.32) | — | |
| SCHEMBL1072262 | 0.89 | — | — | |
| SCHEMBL11613169 | 0.89 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278323-A | Process for preparing chiral dibenzofurans via intramolecular heck reaction | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-01-11 | — | — | US | claimed |
| JP-4182453-A | — | — | None | — | — | JP | disclosed |
| JP-4069375-A | — | — | None | — | — | JP | disclosed |
| CN-118724665-A | Method for constructing chiral alcohol by asymmetric hydrogenation of conjugated ketene | 深圳格林凯特医药技术有限公司 | 2024-10-01 | — | — | CN | disclosed |
| US-20220380309-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-12-01 | — | — | US | disclosed |
| WO-2020117942-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117942-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-11 | — | — | WO | disclosed |
| US-9937186-B2 | Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-04-10 | — | — | US | disclosed |
| US-9937186-B2 | Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-04-10 | — | — | US | disclosed |
| EP-3116860-B1 | SULFONAMIDES DERIVED FROM TRICYCLYL-2-AMINOCYCLOALKANOLS AS ANTICANCER AGENTS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2018-02-07 | — | — | EP | disclosed |
| EP-0559656-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| JP-H04182453-A | OPTICALLY ACTIVE CYCLOHEXYL CARBOXYLATE DERIVATIVE AND ITS PRODUCTION | SANKYO CO LTD | 1992-06-30 | — | — | JP | disclosed |
| WO-1992009592-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| JP-H0469375-A | OPTICALLY ACTIVE CYCLOHEXYLCARBOXYLATE AND ITS PRODUCTION | SANKYO CO LTD | 1992-03-04 | — | — | JP | disclosed |
| CN-1050386-A | Indoles and benzo quinoline, their preparation and they are as anti-arrhythmic | SANKYO CO (JP) | 1991-04-03 | — | — | CN | disclosed |
| EP-0415776-A2 | Indolobenzoquinoline derivatives, their preparation and their use as anti-arrhythmic drugs | Sankyo Company Limited (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0345689-A2 | Process for the preparation of alpha, beta unsaturated alcohols | CIBA-GEIGY AG (CH) | 1989-12-13 | — | — | EP | disclosed |
| EP-0161904-B1 | TETRAHYDROFURANYL AND TETRAHYDROTHIENYL SUBSTITUTED ETHERS | E.R. Squibb & Sons, Inc. (US) | 1989-10-18 | — | — | EP | disclosed |
| EP-0161904-A2 | Tetrahydrofuranyl and tetrahydrothienyl substituted ethers | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |
| US-4521539-A | ANALGESICS, CARDIONVASCULAR AND ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-06-04 | — | — | US | disclosed |