Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.88 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.88 |
| ▸ | OXTR | P30559 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347384 | 0.94 | AVPR1A (1.00) | AVPR1AAVPR2OXTR | |
| SCHEMBL7351779 | 0.83 | AVPR2 (0.71) | AVPR1AAVPR2OXTR | |
| SCHEMBL7347158 | 0.81 | AVPR1A (0.72) | AVPR1AAVPR2OXTR | |
| SCHEMBL8559251 | 0.81 | AVPR2 (0.68) | AVPR1AAVPR2OXTR | |
| SCHEMBL7345796 | 0.80 | AVPR1A (0.64) | AVPR1AAVPR2OXTR | |
| SCHEMBL7352772 | 0.79 | AVPR1A (0.82) | AVPR1AAVPR2OXTR | |
| SCHEMBL7351740 | 0.79 | AVPR2 (0.94) | AVPR1AAVPR2OXTR | |
| SCHEMBL7366451 | 0.79 | AVPR1A (0.74) | AVPR1AAVPR2OXTR | |
| SCHEMBL7351118 | 0.78 | AVPR1A (1.00) | AVPR1AAVPR2OXTR | |
| SCHEMBL8556989 | 0.77 | AVPR1A (0.72) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048484-C | A process for preparing a composition containing benzoheterocycles | OTSUKA PHARMA CO LTD (JP) | 2000-01-19 | — | — | CN | disclosed |
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| CN-1027505-C | Process for preparing benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 1995-01-25 | — | — | CN | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |