Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 14/20 | 0.74 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.74 |
| ▸ | OXTR | P30559 | 1/20 | 0.62 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347384 | 0.85 | AVPR1A (1.00) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL7345883 | 0.82 | MEN1 (0.63) | AVPR1AAVPR2TP53 | |
| SCHEMBL7347271 | 0.79 | AVPR1A (0.88) | AVPR1AAVPR2OXTR | |
| SCHEMBL7352772 | 0.78 | AVPR1A (0.82) | AVPR1AAVPR2OXTR | |
| SCHEMBL7351740 | 0.78 | AVPR2 (0.94) | AVPR1AAVPR2OXTR | |
| SCHEMBL7347158 | 0.78 | AVPR1A (0.72) | AVPR1AAVPR2OXTR | |
| SCHEMBL29383797 | 0.77 | AVPR1A (1.00) | AVPR1AAVPR2OXTR | |
| SCHEMBL7351118 | 0.77 | AVPR1A (1.00) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6991132 | 0.76 | AVPR1A (0.72) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL7343665 | 0.76 | AVPR1A (0.98) | AVPR1AAVPR2OXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | claimed |
| WO-1996022294-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |